Single cell variability of CRISPR‐Cas interference and adaptation

While CRISPR‐Cas defence mechanisms have been studied on a population level, their temporal dynamics and variability in individual cells have remained unknown. Using a microfluidic device, time‐lapse microscopy and mathematical modelling, we studied invader clearance in Escherichia coli across multi...

Descripción completa

Detalles Bibliográficos
Autores principales: McKenzie, Rebecca E, Keizer, Emma M, Vink, Jochem N A, van Lopik, Jasper, Büke, Ferhat, Kalkman, Vera, Fleck, Christian, Tans, Sander J, Brouns, Stan J J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561596/
https://www.ncbi.nlm.nih.gov/pubmed/35467080
http://dx.doi.org/10.15252/msb.202110680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561596/
https://www.ncbi.nlm.nih.gov/pubmed/35467080
http://dx.doi.org/10.15252/msb.202110680

Ejemplares similares