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Trapa Bispinosa Roxb. Inhibits the Insulin-Dependent AKT/WNK1 Pathway to Induce Autophagy in Mice with Type 2 Diabetes

PURPOSE: To elucidate the antiglycation activity of Trapa bispinosa Roxb. extract (TBE) and the related mechanism using a mouse model with type 2 diabetes. MATERIALS AND METHODS: We prepared control mice by giving them a normal diet, leptin-deficient ob/ob mouse (ob/ob mice) with a normal diet (norm...

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Detalles Bibliográficos
Autores principales: Suzuki, Takahiro, Sato, Takehito, Masuhara, Kaori, Tokusanai, Mizuki, Akatsuka, Hisako, Kashikawa, Tomohiro, Suzuki, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561618/
https://www.ncbi.nlm.nih.gov/pubmed/37818405
http://dx.doi.org/10.2147/DMSO.S430132