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Trapa Bispinosa Roxb. Inhibits the Insulin-Dependent AKT/WNK1 Pathway to Induce Autophagy in Mice with Type 2 Diabetes

PURPOSE: To elucidate the antiglycation activity of Trapa bispinosa Roxb. extract (TBE) and the related mechanism using a mouse model with type 2 diabetes. MATERIALS AND METHODS: We prepared control mice by giving them a normal diet, leptin-deficient ob/ob mouse (ob/ob mice) with a normal diet (norm...

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Detalles Bibliográficos
Autores principales:	Suzuki, Takahiro, Sato, Takehito, Masuhara, Kaori, Tokusanai, Mizuki, Akatsuka, Hisako, Kashikawa, Tomohiro, Suzuki, Yasuyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561618/ https://www.ncbi.nlm.nih.gov/pubmed/37818405 http://dx.doi.org/10.2147/DMSO.S430132

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