Mitochondria-targeting EGCG derivatives protect H9c2 cardiomyocytes from H(2)O(2)-induced apoptosis: design, synthesis and biological evaluation

Pathologies related to cardiovascular diseases mostly emerge as a result of oxidative stress buildup in cardiomyocytes. The heavy load of mitochondrial oxidative phosphorylation in cardiac tissues corresponds to a surge in oxidative stress leading to mitochondrial dysfunction and cellular apoptosis....

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Detalles Bibliográficos
Autores principales: Sahadevan, Revathy, Binoy, Anupama, Shajan, Irene, Sadhukhan, Sushabhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561634/
https://www.ncbi.nlm.nih.gov/pubmed/37818277
http://dx.doi.org/10.1039/d3ra04527g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561634/
https://www.ncbi.nlm.nih.gov/pubmed/37818277
http://dx.doi.org/10.1039/d3ra04527g

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