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Mitochondria-targeting EGCG derivatives protect H9c2 cardiomyocytes from H(2)O(2)-induced apoptosis: design, synthesis and biological evaluation
Pathologies related to cardiovascular diseases mostly emerge as a result of oxidative stress buildup in cardiomyocytes. The heavy load of mitochondrial oxidative phosphorylation in cardiac tissues corresponds to a surge in oxidative stress leading to mitochondrial dysfunction and cellular apoptosis....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561634/ https://www.ncbi.nlm.nih.gov/pubmed/37818277 http://dx.doi.org/10.1039/d3ra04527g |