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KSFinder—a knowledge graph model for link prediction of novel phosphorylated substrates of kinases

BACKGROUND: Aberrant protein kinase regulation leading to abnormal substrate phosphorylation is associated with several human diseases. Despite the promise of therapies targeting kinases, many human kinases remain understudied. Most existing computational tools predicting phosphorylation cover less...

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Detalles Bibliográficos
Autores principales: Anandakrishnan, Manju, Ross, Karen E., Chen, Chuming, Shanker, Vijay, Cowart, Julie, Wu, Cathy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561642/
https://www.ncbi.nlm.nih.gov/pubmed/37818330
http://dx.doi.org/10.7717/peerj.16164