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UNC-116 and UNC-16 function with the NEKL-3 kinase to promote axon targeting

KIF5C is a kinesin-1 heavy chain that has been associated with neurodevelopmental disorders. Although the roles of kinesin-1 in axon transport are well known, little is known about how it regulates axon targeting. We report that UNC-116/KIF5C functions with the NEKL-3/NEK6/7 kinase to promote axon t...

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Detalles Bibliográficos
Autores principales: Drozd, Cody J., Quinn, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561693/
https://www.ncbi.nlm.nih.gov/pubmed/37756604
http://dx.doi.org/10.1242/dev.201654