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A phase I study of autologous mesenchymal stromal cells for severe steroid-dependent nephrotic syndrome

BACKGROUND: Severe forms of idiopathic nephrotic syndrome (INS) require prolonged immunosuppressive therapies and repeated courses of high-dose glucocorticoids. Mesenchymal stromal cells (MSCs) have promising immunomodulatory properties that may be employed therapeutically to reduce patient exposure...

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Detalles Bibliográficos
Autores principales: Vivarelli, Marina, Colucci, Manuela, Algeri, Mattia, Zotta, Federica, Emma, Francesco, L’Erario, Ines, Busutti, Marco, Rota, Stefano, Capelli, Chiara, Introna, Martino, Todeschini, Marta, Casiraghi, Federica, Perna, Annalisa, Peracchi, Tobia, De Salvo, Andrea, Rubis, Nadia, Locatelli, Franco, Remuzzi, Giuseppe, Ruggenenti, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561718/
https://www.ncbi.nlm.nih.gov/pubmed/37561590
http://dx.doi.org/10.1172/jci.insight.169424