Alternative polyadenylation reprogramming of MORC2 induced by NUDT21 loss promotes KIRC carcinogenesis

Alternative polyadenylation (APA), a posttranscriptional mechanism of gene expression via determination of 3′UTR length, has an emerging role in carcinogenesis. Although abundant APA reprogramming is found in kidney renal clear cell carcinoma (KIRC), which is one of the major malignancies, whether A...

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Detalles Bibliográficos
Autores principales: Tan, Yuqin, Zheng, Tong, Su, Zijun, Chen, Min, Chen, Suxiang, Zhang, Rui, Wang, Ruojiao, Li, Ke, Na, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561724/
https://www.ncbi.nlm.nih.gov/pubmed/37737260
http://dx.doi.org/10.1172/jci.insight.162893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561724/
https://www.ncbi.nlm.nih.gov/pubmed/37737260
http://dx.doi.org/10.1172/jci.insight.162893

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