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Preexisting immunity restricts mucosal antibody recognition of SARS-CoV-2 and Fc profiles during breakthrough infections

Understanding mucosal antibody responses from SARS-CoV-2 infection and/or vaccination is crucial to develop strategies for longer term immunity, especially against emerging viral variants. We profiled serial paired mucosal and plasma antibodies from COVID-19 vaccinated only vaccinees (vaccinated, un...

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Detalles Bibliográficos
Autores principales: Selva, Kevin J., Ramanathan, Pradhipa, Haycroft, Ebene R., Reynaldi, Arnold, Cromer, Deborah, Tan, Chee Wah, Wang, Lin-Fa, Wines, Bruce D., Hogarth, P. Mark, Downie, Laura E., Davis, Samantha K., Purcell, Ruth A., Kent, Helen E., Juno, Jennifer A., Wheatley, Adam K., Davenport, Miles P., Kent, Stephen J., Chung, Amy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561726/
https://www.ncbi.nlm.nih.gov/pubmed/37737263
http://dx.doi.org/10.1172/jci.insight.172470