Cardiac gene therapy treats diabetic cardiomyopathy and lowers blood glucose

Diabetic cardiomyopathy, an increasingly global epidemic and a major cause of heart failure with preserved ejection fraction (HFpEF), is associated with hyperglycemia, insulin resistance, and intracardiomyocyte calcium mishandling. Here we identify that, in db/db mice with type 2 diabetes–induced HF...

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Detalles Bibliográficos
Autores principales: Li, Jing, Richmond, Bradley, Cluntun, Ahmad A., Bia, Ryan, Walsh, Maureen A., Shaw, Kikuyo, Symons, J. David, Franklin, Sarah, Rutter, Jared, Funai, Katsuhiko, Shaw, Robin M., Hong, TingTing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561727/
https://www.ncbi.nlm.nih.gov/pubmed/37639557
http://dx.doi.org/10.1172/jci.insight.166713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561727/
https://www.ncbi.nlm.nih.gov/pubmed/37639557
http://dx.doi.org/10.1172/jci.insight.166713

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