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TRAF4 is crucial for ST2(+) memory Th2 cell expansion in IL-33–driven airway inflammation
Tumor necrosis factor receptor–associated factor 4 (TRAF4) is an important regulator of type 2 responses in the airway; however, the underlying cellular and molecular mechanisms remain elusive. Herein, we generated T cell–specific TRAF4-deficient (CD4-cre Traf4(fl/fl)) mice and investigated the role...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561728/ https://www.ncbi.nlm.nih.gov/pubmed/37607012 http://dx.doi.org/10.1172/jci.insight.169736 |