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TRAF4 is crucial for ST2(+) memory Th2 cell expansion in IL-33–driven airway inflammation

Tumor necrosis factor receptor–associated factor 4 (TRAF4) is an important regulator of type 2 responses in the airway; however, the underlying cellular and molecular mechanisms remain elusive. Herein, we generated T cell–specific TRAF4-deficient (CD4-cre Traf4(fl/fl)) mice and investigated the role...

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Detalles Bibliográficos
Autores principales: Xiao, Jianxin, Chen, Xing, Liu, Weiwei, Qian, Wen, Bulek, Katarzyna, Hong, Lingzi, Miller-Little, William, Li, Xiaoxia, Liu, Caini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561728/
https://www.ncbi.nlm.nih.gov/pubmed/37607012
http://dx.doi.org/10.1172/jci.insight.169736

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