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Role of succinate in airway epithelial cell regulation following traumatic lung injury

Lung contusion and gastric aspiration (LC and GA) are major risk factors for developing acute respiratory distress following trauma. Hypoxia from lung injury is mainly regulated by hypoxia-inducible factor 1α (HIF-1α). Published data from our group indicate that HIF-1α regulation in airway epithelia...

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Detalles Bibliográficos
Autores principales: Suresh, Madathilparambil V., Aktay, Sinan, Yalamanchili, George, Solanki, Sumeet, Sathyarajan, Dily Thazhath, Arnipalli, Manikanta Swamy, Pennathur, Subramaniam, Raghavendran, Krishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561732/
https://www.ncbi.nlm.nih.gov/pubmed/37737265
http://dx.doi.org/10.1172/jci.insight.166860