Cargando…

Role of succinate in airway epithelial cell regulation following traumatic lung injury

Lung contusion and gastric aspiration (LC and GA) are major risk factors for developing acute respiratory distress following trauma. Hypoxia from lung injury is mainly regulated by hypoxia-inducible factor 1α (HIF-1α). Published data from our group indicate that HIF-1α regulation in airway epithelia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suresh, Madathilparambil V., Aktay, Sinan, Yalamanchili, George, Solanki, Sumeet, Sathyarajan, Dily Thazhath, Arnipalli, Manikanta Swamy, Pennathur, Subramaniam, Raghavendran, Krishnan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561732/ https://www.ncbi.nlm.nih.gov/pubmed/37737265 http://dx.doi.org/10.1172/jci.insight.166860

Ejemplares similares

Hypoxia-Inducible Factor 1α and Its Role in Lung Injury: Adaptive or Maladaptive
por: Suresh, Madathilparambil V., et al.
Publicado: (2023)

Hypoxia‐inducible factor (HIF)‐1α‐induced regulation of lung injury in pulmonary aspiration is mediated through NF‐kB
por: Suresh, Madathilparambil V., et al.
Publicado: (2022)

Electroporation-mediated Delivery of the FER Gene in the Resolution of Trauma-related Fatal Pneumonia
por: Dolgachev, Vladislav A., et al.
Publicado: (2016)

The Epithelial to Mesenchymal Transition in Colorectal Cancer Progression: The Emerging Role of Succinate Dehydrogenase Alterations and Succinate Accumulation
por: Turano, Mimmo, et al.
Publicado: (2023)

Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage
por: Abdullah, Sarah, et al.
Publicado: (2023)

Bis(melaminium) succinate succinic acid monosolvate dihydrate
por: Froschauer, Barbara, et al.
Publicado: (2012)

Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism
por: Aspuria, Paul-Joseph P, et al.
Publicado: (2014)

Bis(ethanolaminium) succinate–succinic acid (1/1)
por: Zhang, Miao, et al.
Publicado: (2011)

Bis(4-methylimidazolium) succinate succinic acid solvate
por: Du, Guihuan, et al.
Publicado: (2009)

Bis(2-aminothiazolium) succinate succinic acid
por: Fun, Hoong-Kun, et al.
Publicado: (2009)

Effect of Hydroxyl Monomers on the Enzymatic Degradation of Poly(ethylene succinate), Poly(butylene succinate), and Poly(hexylene succinate)
por: Bai, Zhenhui, et al.
Publicado: (2018)

Urinary 2-Hydroxyglutarate Enantiomers Are Markedly Elevated in a Murine Model of Type 2 Diabetic Kidney Disease
por: Baek, Judy, et al.
Publicado: (2021)

Healthcare Cost and Outcomes Associated With Surgical Site Infection and Patient Outcomes in Low- and Middle-Income Countries
por: Costabella, Fernando, et al.
Publicado: (2023)

Focally administered succinate improves cerebral metabolism in traumatic brain injury patients with mitochondrial dysfunction
por: Khellaf, Abdelhakim, et al.
Publicado: (2021)

The PLOD2/succinate axis regulates the epithelial–mesenchymal plasticity and cancer cell stemness
por: Tong, Yuxin, et al.
Publicado: (2023)

The balance of powers: Redox regulation of fibrogenic pathways in kidney injury
por: Okamura, Daryl M., et al.
Publicado: (2015)

Response to Comment on Mathew et al. Therapeutic Lifestyle Changes Improve HDL Function by Inhibiting Myeloperoxidase-Mediated Oxidation in Patients With Metabolic Syndrome. Diabetes Care 2018;41:2431–2437
por: Mathew, Anna V., et al.
Publicado: (2019)

Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas
por: Matlac, Dieter M., et al.
Publicado: (2021)

The COVID-19 Pandemic Impact on Pediatric Endoscopies in a Single Center
por: Moyer, Shannon, et al.
Publicado: (2022)

Lack of Major Genome-Wide DNA Methylation Changes in Succinate-Treated Human Epithelial Cells
por: Cui, Wei, et al.
Publicado: (2022)

Crystal structure of the bis(cyclohexylammonium) succinate succinic acid salt adduct
por: Sarr, Modou, et al.
Publicado: (2015)

Succinate Dehydrogenase, Succinate, and Superoxides: A Genetic, Epigenetic, Metabolic, Environmental Explosive Crossroad
por: Bénit, Paule, et al.
Publicado: (2022)

Hydrolysis of lignocellulose to succinic acid: a review of treatment methods and succinic acid applications
por: Zhou, Shuzhen, et al.
Publicado: (2023)

Electroporation-mediated Delivery of FER Gene Enhances Innate Immune Response and Improves Survival in a Murine Model of Pneumonia
por: Dolgachev, Vladislav, et al.
Publicado: (2018)

Making Succinate More Successful
por: Potera, Carol
Publicado: (2005)

Aminoguanidinium hydrogen succinate
por: Murugavel, S., et al.
Publicado: (2009)

Succinate: An initiator in tumorigenesis and progression
por: Zhao, Ting, et al.
Publicado: (2017)

Tafenoquine succinate for malaria prevention
Publicado: (2019)

A Case of Traumatic Diaphragmatic Hernia
por: Swamy, Narayana
Publicado: (1899)

Succinate dehydrogenase‐deficient malignant paraganglioma complicated by succinate dehydrogenase‐deficient renal cell carcinoma
por: Yamaguchi, Yoshitomo, et al.
Publicado: (2022)

Nitric oxide gas phase release in human small airway epithelial cells
por: Jiang, Jingjing, et al.
Publicado: (2009)

The epithelial cholinergic system of the airways
por: Kummer, W., et al.
Publicado: (2008)

Airway Epithelial Innate Immunity
por: Johnston, Sebastian L., et al.
Publicado: (2021)

Airway Epithelial Dysfunction in Asthma: Relevant to Epidermal Growth Factor Receptors and Airway Epithelial Cells
por: Inoue, Hideki, et al.
Publicado: (2020)

Antibiotics in Food Chain: The Consequences for Antibiotic Resistance
por: Kumar, Shashi B., et al.
Publicado: (2020)

Development of α-Tocopherol Succinate-Based Nanostructured Lipid Carriers for Delivery of Paclitaxel
por: Marathe, Sushrut, et al.
Publicado: (2022)

A183 SUCCINATE IN THE RELATIONSHIP BETWEEN INFLAMMATORY BOWEL DISEASE AND OBESITY IN SUCCINATE RECEPTOR DEFICIENT MICE
por: Arsenault, A M, et al.
Publicado: (2022)

The effect of succinate on brain NADH/NAD(+) redox state and high energy phosphate metabolism in acute traumatic brain injury
por: Stovell, Matthew G., et al.
Publicado: (2018)

The functional indexes of RBCs and microcirculation in the traumatic brain injury with the action of 2-ethil-6-methil-3-hydroxypiridin succinate
por: Polozova Anastasia, V., et al.
Publicado: (2021)

Ethylene Diamine Tetra Acetate-Induced Pseudo Thrombocytopenia (EDTA-PTCP) in an Adolescent: A Case Report
por: Tangella, Adarsh Vardhan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7t6us15tepsbt44t0rgatg2nta