OSWG Recommended Approaches to the Nonclinical Pharmacokinetic (ADME) Characterization of Therapeutic Oligonucleotides

This white paper summarizes the recommendations of the absorption, distribution, metabolism, and excretion (ADME) Subcommittee of the Oligonucleotide Safety Working Group for the characterization of absorption, distribution, metabolism, and excretion of oligonucleotide (ON) therapeutics in nonclinic...

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Detalles Bibliográficos
Autores principales: Berman, Cindy L., Antonsson, Madeleine, Batkai, Sandor, Bosgra, Sieto, Chopda, Girish R., Driessen, Wouter, Foy, Jeffrey, Hassan, Chopie, Hu, Xiao Shelley, Jang, Hyun Gyung, Meena,  , Sanseverino, Mark, Thum, Thomas, Wang, Yanfeng, Wild, Martin, Wu, Jing-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Issues in Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561745/
https://www.ncbi.nlm.nih.gov/pubmed/37590469
http://dx.doi.org/10.1089/nat.2023.0011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561745/
https://www.ncbi.nlm.nih.gov/pubmed/37590469
http://dx.doi.org/10.1089/nat.2023.0011

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