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Loss of Otopetrin 1 affects thermoregulation during fasting in mice
OBJECTIVE: Otopetrin 1 (OTOP1) is a proton channel that is highly expressed in brown adipose tissue. We examined the physiology of Otop1(-/-) mice, which lack functional OTOP1. METHODS: Mice were studied by indirect calorimetry and telemetric ambulatory body temperature monitoring. Mitochondrial fun...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561838/ https://www.ncbi.nlm.nih.gov/pubmed/37812612 http://dx.doi.org/10.1371/journal.pone.0292610 |