Hydroxyurea does not reverse functional alterations of the nitric oxide-cGMP pathway associated with priapism phenotype in corpus cavernosum from sickle cell mouse

Sickle cell disease (SCD) is a genetic disorder that has been associated with priapism. The role of hydroxyurea, a common SCD therapy, in influencing the nitric oxide (NO)-cGMP pathway and its effect on priapism is unclear. To investigate the effect of hydroxyurea treatment on smooth muscle relaxati...

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Detalles Bibliográficos
Autores principales: Pereira, Dalila Andrade, Pereira, Danillo Andrade, da Silva Pereira, Pamela, Silveira, Tammyris Helena Rebecchi, Calmasini, Fabiano Beraldi, Reis, Leonardo Oliveira, Costa, Fernando Ferreira, Silva, Fábio Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561851/
https://www.ncbi.nlm.nih.gov/pubmed/37812620
http://dx.doi.org/10.1371/journal.pone.0292706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10561851/
https://www.ncbi.nlm.nih.gov/pubmed/37812620
http://dx.doi.org/10.1371/journal.pone.0292706

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