Transcriptomic analysis reveals partial epithelial–mesenchymal transition and inflammation as common pathogenic mechanisms in hypertensive nephrosclerosis and Type 2 diabetic nephropathy

Hypertensive nephrosclerosis (HN) and Type 2 diabetic nephropathy (T2DN) are the leading causes of chronic kidney disease (CKD). To explore shared pathogenetic mechanisms, we analyzed transcriptomes of kidney biopsies from patients with HN or T2DN. Total RNA was extracted from 10 μm whole kidney sec...

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Detalles Bibliográficos
Autores principales: Nordbø, Ole Petter, Landolt, Lea, Eikrem, Øystein, Scherer, Andreas, Leh, Sabine, Furriol, Jessica, Apeland, Terje, Mydel, Piotr, Marti, Hans‐Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562137/
https://www.ncbi.nlm.nih.gov/pubmed/37813528
http://dx.doi.org/10.14814/phy2.15825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562137/
https://www.ncbi.nlm.nih.gov/pubmed/37813528
http://dx.doi.org/10.14814/phy2.15825

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