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Mutation rates and fitness consequences of mosaic chromosomal alterations in blood
Mosaic chromosomal alterations (mCAs) are common in cancers and can arise decades before diagnosis. A quantitative understanding of the rate at which these events occur, and their functional consequences, could improve cancer risk prediction and our understanding of somatic evolution. Using mCA clon...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group US
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562253/ https://www.ncbi.nlm.nih.gov/pubmed/37697102 http://dx.doi.org/10.1038/s41588-023-01490-z |