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Sclerostin antibody improves alveolar bone quality in the Hyp mouse model of X-linked hypophosphatemia (XLH)

X-linked hypophosphatemia (XLH) is a rare disease of elevated fibroblast growth factor 23 (FGF23) production that leads to hypophosphatemia and impaired mineralization of bone and teeth. The clinical manifestations of XLH include a high prevalence of dental abscesses and periodontal disease, likely...

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Detalles Bibliográficos
Autores principales: Carpenter, Kelsey A., Alkhatib, Delia O., Dulion, Bryan A., Guirado, Elizabeth, Patel, Shreya, Chen, Yinghua, George, Anne, Ross, Ryan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562382/
https://www.ncbi.nlm.nih.gov/pubmed/37813865
http://dx.doi.org/10.1038/s41368-023-00252-1