Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release

Microglial reactivity is a pathological hallmark in many neurodegenerative diseases. During stimulation, microglia undergo complex morphological changes, including loss of their characteristic ramified morphology, which is routinely used to detect and quantify inflammation in the brain. However, the...

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Detalles Bibliográficos
Autores principales: Adrian, Max, Weber, Martin, Tsai, Ming-Chi, Glock, Caspar, Kahn, Olga I., Phu, Lilian, Cheung, Tommy K., Meilandt, William J., Rose, Christopher M., Hoogenraad, Casper C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562429/
https://www.ncbi.nlm.nih.gov/pubmed/37813836
http://dx.doi.org/10.1038/s41467-023-41891-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562429/
https://www.ncbi.nlm.nih.gov/pubmed/37813836
http://dx.doi.org/10.1038/s41467-023-41891-6

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