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Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release
Microglial reactivity is a pathological hallmark in many neurodegenerative diseases. During stimulation, microglia undergo complex morphological changes, including loss of their characteristic ramified morphology, which is routinely used to detect and quantify inflammation in the brain. However, the...
Autores principales: | Adrian, Max, Weber, Martin, Tsai, Ming-Chi, Glock, Caspar, Kahn, Olga I., Phu, Lilian, Cheung, Tommy K., Meilandt, William J., Rose, Christopher M., Hoogenraad, Casper C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562429/ https://www.ncbi.nlm.nih.gov/pubmed/37813836 http://dx.doi.org/10.1038/s41467-023-41891-6 |
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