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CDCA8 promotes bladder cancer survival by stabilizing HIF1α expression under hypoxia

Hypoxia is an essential hallmark of solid tumors and HIF1α is a central regulator of tumor cell adaptation and survival in the hypoxic environment. In this study, we explored the biological functions of cell cycle division-related gene 8 (CDCA8) in bladder cancer (BCa) cells in the hypoxic settings....

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Detalles Bibliográficos
Autores principales: Zhou, Qiang, Huang, Wei, Xiong, Jing, Guo, Biao, Wang, Xinghuan, Guo, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562466/
https://www.ncbi.nlm.nih.gov/pubmed/37813876
http://dx.doi.org/10.1038/s41419-023-06189-x