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Single-cell allele-specific expression analysis reveals dynamic and cell-type-specific regulatory effects

Differential allele-specific expression (ASE) is a powerful tool to study context-specific cis-regulation of gene expression. Such effects can reflect the interaction between genetic or epigenetic factors and a measured context or condition. Single-cell RNA sequencing (scRNA-seq) allows the measurem...

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Detalles Bibliográficos
Autores principales: Qi, Guanghao, Strober, Benjamin J., Popp, Joshua M., Keener, Rebecca, Ji, Hongkai, Battle, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562474/
https://www.ncbi.nlm.nih.gov/pubmed/37813843
http://dx.doi.org/10.1038/s41467-023-42016-9