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Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis

Liver fibrosis results from chronic liver injury triggered by factors such as viral infection, excess alcohol intake, and lipid accumulation. However, the mechanisms underlying liver fibrosis are not fully understood. Here, we demonstrate that the expression of fibroblast growth factor 18 (Fgf18) is...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Yuichi, Seki, Takao, Kobayashi, Kenta, Komazawa-Sakon, Sachiko, Shichino, Shigeyuki, Nishina, Takashi, Fukuhara, Kyoko, Ikejima, Kenichi, Nagai, Hidenari, Igarashi, Yoshinori, Ueha, Satoshi, Oikawa, Akira, Tsurusaki, Shinya, Yamazaki, Soh, Nishiyama, Chiharu, Mikami, Tetuo, Yagita, Hideo, Okumura, Ko, Kido, Taketomo, Miyajima, Atsushi, Matsushima, Kouji, Imasaka, Mai, Araki, Kimi, Imamura, Toru, Ohmuraya, Masaki, Tanaka, Minoru, Nakano, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562492/
https://www.ncbi.nlm.nih.gov/pubmed/37813881
http://dx.doi.org/10.1038/s41467-023-42058-z