Cargando…

TOAST: A novel method for identifying topologically associated domains based on graph auto-encoders and clustering()

Topologically associated domains (TADs) play a pivotal role in disease detection. This study introduces a novel TADs recognition approach named TOAST, leveraging graph auto-encoders and clustering techniques. TOAST conceptualizes each genomic bin as a node of a graph and employs the Hi-C contact mat...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Haiyan, Zhang, Dawei, Zhang, Xiaotong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562672/
https://www.ncbi.nlm.nih.gov/pubmed/37822562
http://dx.doi.org/10.1016/j.csbj.2023.09.019