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TOAST: A novel method for identifying topologically associated domains based on graph auto-encoders and clustering()
Topologically associated domains (TADs) play a pivotal role in disease detection. This study introduces a novel TADs recognition approach named TOAST, leveraging graph auto-encoders and clustering techniques. TOAST conceptualizes each genomic bin as a node of a graph and employs the Hi-C contact mat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562672/ https://www.ncbi.nlm.nih.gov/pubmed/37822562 http://dx.doi.org/10.1016/j.csbj.2023.09.019 |