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Persistent homology analysis of type 2 diabetes genome-wide association studies in protein–protein interaction networks

Genome-wide association studies (GWAS) involving increasing sample sizes have identified hundreds of genetic variants associated with complex diseases, such as type 2 diabetes (T2D); however, it is unclear how GWAS hits form unique topological structures in protein–protein interaction (PPI) networks...

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Detalles Bibliográficos
Autor principal: Song, Euijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562725/
https://www.ncbi.nlm.nih.gov/pubmed/37823029
http://dx.doi.org/10.3389/fgene.2023.1270185