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Role of the epithelial barrier in intestinal fibrosis associated with inflammatory bowel disease: relevance of the epithelial-to mesenchymal transition

In inflammatory bowel disease (IBD), chronic inflammation in the gastrointestinal tract can lead to tissue damage and remodelling, which can ultimately result in fibrosis. Prolonged injury and inflammation can trigger the activation of fibroblasts and extracellular matrix (ECM) components. As fibros...

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Detalles Bibliográficos
Autores principales: Macias-Ceja, Dulce C., Mendoza-Ballesteros, M. Teresa, Ortega-Albiach, María, Barrachina, M. Dolores, Ortiz-Masià, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562728/
https://www.ncbi.nlm.nih.gov/pubmed/37822869
http://dx.doi.org/10.3389/fcell.2023.1258843