EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway

Pancreatic beta cells produce and secrete insulin as a response to rises in blood glucose. Despite the advances in understanding glucose-regulated insulin transcription and translation the mechanisms triggering the synthesis of new insulin molecules are still incompletely described. In this report,...

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Detalles Bibliográficos
Autores principales: (Flintoaca) Alexandru, Petruta R., Chiritoiu, Gabriela N., Lixandru, Daniela, Zurac, Sabina, Ionescu-Targoviste, Constantin, Petrescu, Stefana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562789/
https://www.ncbi.nlm.nih.gov/pubmed/37822496
http://dx.doi.org/10.1016/j.isci.2023.107956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562789/
https://www.ncbi.nlm.nih.gov/pubmed/37822496
http://dx.doi.org/10.1016/j.isci.2023.107956

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