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EDEM1 regulates the insulin mRNA level by inhibiting the endoplasmic reticulum stress-induced IRE1/JNK/c-Jun pathway

Pancreatic beta cells produce and secrete insulin as a response to rises in blood glucose. Despite the advances in understanding glucose-regulated insulin transcription and translation the mechanisms triggering the synthesis of new insulin molecules are still incompletely described. In this report,...

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Detalles Bibliográficos
Autores principales:	(Flintoaca) Alexandru, Petruta R., Chiritoiu, Gabriela N., Lixandru, Daniela, Zurac, Sabina, Ionescu-Targoviste, Constantin, Petrescu, Stefana M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562789/ https://www.ncbi.nlm.nih.gov/pubmed/37822496 http://dx.doi.org/10.1016/j.isci.2023.107956

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