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KMT2D suppresses Sonic hedgehog-driven medulloblastoma progression and metastasis

The major cause of treatment failure and mortality among medulloblastoma patients is metastasis intracranially or along the spinal cord. The molecular mechanisms driving tumor metastasis in Sonic hedgehog-driven medulloblastoma (SHH-MB) patients, however, remain largely unknown. In this study we def...

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Detalles Bibliográficos
Autores principales: Sanghrajka, Reeti Mayur, Koche, Richard, Medrano, Hector, El Nagar, Salsabiel, Stephen, Daniel N., Lao, Zhimin, Bayin, N. Sumru, Ge, Kai, Joyner, Alexandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562805/
https://www.ncbi.nlm.nih.gov/pubmed/37822508
http://dx.doi.org/10.1016/j.isci.2023.107831