Cargando…
KMT2D suppresses Sonic hedgehog-driven medulloblastoma progression and metastasis
The major cause of treatment failure and mortality among medulloblastoma patients is metastasis intracranially or along the spinal cord. The molecular mechanisms driving tumor metastasis in Sonic hedgehog-driven medulloblastoma (SHH-MB) patients, however, remain largely unknown. In this study we def...
Autores principales: | Sanghrajka, Reeti Mayur, Koche, Richard, Medrano, Hector, El Nagar, Salsabiel, Stephen, Daniel N., Lao, Zhimin, Bayin, N. Sumru, Ge, Kai, Joyner, Alexandra L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562805/ https://www.ncbi.nlm.nih.gov/pubmed/37822508 http://dx.doi.org/10.1016/j.isci.2023.107831 |
Ejemplares similares
-
CSF1R Inhibition Depletes Tumor-Associated Macrophages and Attenuates Tumor Progression in a Mouse Sonic Hedgehog-Medulloblastoma Model
por: Tan, I-Li, et al.
Publicado: (2020) -
Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma
por: Brun, Sonja N., et al.
Publicado: (2014) -
Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma
por: Jenkins, Noah C, et al.
Publicado: (2014) -
HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma
por: Bell, Jonathan B., et al.
Publicado: (2018) -
A Sexually Dimorphic Role for STAT3 in Sonic Hedgehog Medulloblastoma
por: White, Christine L., et al.
Publicado: (2019)