Efficacy and Safety of XEN1101, a Novel Potassium Channel Opener, in Adults With Focal Epilepsy: A Phase 2b Randomized Clinical Trial

IMPORTANCE: Many patients with focal epilepsy experience seizures despite treatment with currently available antiseizure medications (ASMs) and may benefit from novel therapeutics. OBJECTIVE: To evaluate the efficacy and safety of XEN1101, a novel small-molecule selective Kv7.2/Kv7.3 potassium chann...

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Detalles Bibliográficos
Autores principales: French, Jacqueline A., Porter, Roger J., Perucca, Emilio, Brodie, Martin J., Rogawski, Michael A., Pimstone, Simon, Aycardi, Ernesto, Harden, Cynthia, Qian, Jenny, Luzon Rosenblut, Constanza, Kenney, Christopher, Beatch, Gregory N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562989/
https://www.ncbi.nlm.nih.gov/pubmed/37812429
http://dx.doi.org/10.1001/jamaneurol.2023.3542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562989/
https://www.ncbi.nlm.nih.gov/pubmed/37812429
http://dx.doi.org/10.1001/jamaneurol.2023.3542

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