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Exosomes released from PD-L1(+) tumor associated macrophages promote peritoneal metastasis of epithelial ovarian cancer by up-regulating T cell lipid metabolism

Epithelial ovarian cancer (EOC) tends to metastasize to the peritoneum, and the prognosis of patients is poor. In the peritoneum of patients with EOC, TAMs (tumor associated macrophages) regulate the imbalance of T cell ratio and promote the progression and metastasis of EOC. However, the mechanism...

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Detalles Bibliográficos
Autores principales: Ma, Jun, Cen, Qianqian, Wang, Qingzhu, Liu, Li, Zhou, Jieru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563010/
https://www.ncbi.nlm.nih.gov/pubmed/37822876
http://dx.doi.org/10.1016/j.bbrep.2023.101542