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Lack of thyroid hormone receptor beta is not detrimental for non-alcoholic steatohepatitis progression

Agonists for thyroid hormone receptor β (TRβ) show promise in preclinical studies and clinical trials to improve non-alcoholic fatty liver disease. A recent study on human livers, however, revealed reduced TRβ expression in non-alcoholic steatohepatitis (NASH), indicating a developing thyroid hormon...

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Detalles Bibliográficos
Autores principales: Lopez-Alcantara, Nuria, Oelkrug, Rebecca, Sentis, Sarah Christine, Kirchner, Henriette, Mittag, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563054/
https://www.ncbi.nlm.nih.gov/pubmed/37822510
http://dx.doi.org/10.1016/j.isci.2023.108064