Cargando…

Lack of thyroid hormone receptor beta is not detrimental for non-alcoholic steatohepatitis progression

Agonists for thyroid hormone receptor β (TRβ) show promise in preclinical studies and clinical trials to improve non-alcoholic fatty liver disease. A recent study on human livers, however, revealed reduced TRβ expression in non-alcoholic steatohepatitis (NASH), indicating a developing thyroid hormon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lopez-Alcantara, Nuria, Oelkrug, Rebecca, Sentis, Sarah Christine, Kirchner, Henriette, Mittag, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563054/ https://www.ncbi.nlm.nih.gov/pubmed/37822510 http://dx.doi.org/10.1016/j.isci.2023.108064

Ejemplares similares

Thyroid hormones in the regulation of brown adipose tissue thermogenesis
por: Sentis, Sarah Christine, et al.
Publicado: (2021)

Reduced expression of thyroid hormone receptor β in human nonalcoholic steatohepatitis
por: Krause, Christin, et al.
Publicado: (2018)

Resistance to thyroid hormone induced tachycardia in RTHα syndrome
por: Dore, Riccardo, et al.
Publicado: (2023)

Too Much Too Soon—Tissue-specific Inactivation of Deiodinase Type 3 Prematurely Exposes Brown Fat to Thyroid Hormone
por: Oelkrug, Rebecca, et al.
Publicado: (2022)

The Detrimental Role of Regulatory T Cells in Nonalcoholic Steatohepatitis
por: Dywicki, Janine, et al.
Publicado: (2021)

An improved method for the precise unravelment of non-shivering brown fat thermokinetics
por: Oelkrug, Rebecca, et al.
Publicado: (2021)

Dwarfism and insulin resistance in male offspring caused by α1-adrenergic antagonism during pregnancy
por: Oelkrug, Rebecca, et al.
Publicado: (2017)

Maternal thyroid hormone receptor β activation in mice sparks brown fat thermogenesis in the offspring
por: Oelkrug, Rebecca, et al.
Publicado: (2023)

Thyroid Hormones and Thyromimetics: A New Approach to Nonalcoholic Steatohepatitis?
por: Sinha, Rohit A., et al.
Publicado: (2020)

Association between Thyroid Hormones and Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis in Obese Individuals Undergoing Bariatric Surgery
por: Ashraf Ganjooei, Narges, et al.
Publicado: (2022)

Lack of VMP1 impairs hepatic lipoprotein secretion and promotes non-alcoholic steatohepatitis
por: Jiang, Xiaoxiao, et al.
Publicado: (2022)

Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)
por: Luong, Xuan G., et al.
Publicado: (2020)

Non-alcoholic steatohepatitis-related liver tumorigenesis is suppressed in mice lacking hepatic retinoid storage
por: Ideta, Takayasu, et al.
Publicado: (2017)

Synergistic and Detrimental Effects of Alcohol Intake on Progression of Liver Steatosis
por: Di Ciaula, Agostino, et al.
Publicado: (2022)

Thyroid-stimulating hormone is associated with nonalcoholic steatohepatitis in patients with chronic hepatitis B
por: Liu, Liang, et al.
Publicado: (2019)

Dopamine receptor D1- and D2-agonists do not spark brown adipose tissue thermogenesis in mice
por: Raffaelli, Francesca-Maria, et al.
Publicado: (2020)

The Role of Epigenetic Changes in the Progression of Alcoholic Steatohepatitis
por: Kim, Hyeong Geug, et al.
Publicado: (2021)

Combined alcoholic and non-alcoholic steatohepatitis
por: Ntandja Wandji, Line Carolle, et al.
Publicado: (2020)

The Detrimental Effects of Alcohol and Cannabinoids on Cardiovascular Function
por: Montecucco, Fabrizio, et al.
Publicado: (2019)

Thyroid Hormones Regulate Selenoprotein Expression and Selenium Status in Mice
por: Mittag, Jens, et al.
Publicado: (2010)

Fructose and Non-Alcoholic Steatohepatitis
por: Roeb, Elke, et al.
Publicado: (2021)

Statins in Non-alcoholic Steatohepatitis
por: Torres-Peña, Jose D., et al.
Publicado: (2021)

The expression and secretion of vimentin in the progression of non-alcoholic steatohepatitis
por: Lee, Su Jin, et al.
Publicado: (2014)

Natural Progression of Non-Alcoholic Steatohepatitis to Hepatocellular Carcinoma
por: Ramai, Daryl, et al.
Publicado: (2021)

Identification of thyroid hormone response elements in vivo using mice expressing a tagged thyroid hormone receptor α1
por: Dudazy-Gralla, Susi, et al.
Publicado: (2013)

Role of Alcohol Metabolism in Non-Alcoholic Steatohepatitis
por: Baker, Susan S., et al.
Publicado: (2010)

Resistance to thyroid hormone due to a novel mutation of thyroid hormone receptor beta gene
por: Lee, Jae Hee, et al.
Publicado: (2014)

A rare mutation of thyroid hormone receptor beta gene in thyroid hormone resistance syndrome
por: Del Prete, Michela, et al.
Publicado: (2021)

SUN-546 Coexistent Resistance to Thyroid Hormone Beta and Viral Thyroiditis
por: Golubic, Rajna, et al.
Publicado: (2019)

Effects of sildenafil treatment on thermogenesis and glucose homeostasis in diet-induced obese mice
por: Johann, Kornelia, et al.
Publicado: (2018)

Will it ever change? Lack of parental leave and its detrimental effects on maternal well-being
por: Jefferson, Erin E.Y.
Publicado: (2023)

Liver Fibrogenesis in Non-Alcoholic Steatohepatitis
por: Bian, Zhaolian, et al.
Publicado: (2012)

Therapeutic approaches for non-alcoholic steatohepatitis
por: Van Gaal, Luc F., et al.
Publicado: (2021)

TRα2—An Untuned Second Fiddle or Fine-Tuning Thyroid Hormone Action?
por: Hönes, Georg Sebastian, et al.
Publicado: (2022)

Resistance to Thyroid Hormone with Missense Mutation (V349M) in the Thyroid Hormone Receptor Beta Gene
por: Kim, Ji Yon, et al.
Publicado: (2008)

The Mutant Thyroid Hormone Receptor Beta R320P Causes Syndrome of Resistance to Thyroid Hormone
por: Kimura, Tetsuya, et al.
Publicado: (2018)

Resistance to Thyroid Hormone Beta: A Focused Review
por: Pappa, Theodora, et al.
Publicado: (2021)

Is beta-carotene consumption associated with thyroid hormone levels?
por: Farasati Far, Bahareh, et al.
Publicado: (2023)

Resistance to thyroid hormone beta coexisting with papillary thyroid carcinoma—two case reports of a thyroid hormone receptor beta gene mutation and a literature review
por: Fang, Yingxin, et al.
Publicado: (2022)

Alcoholic and non-alcoholic steatohepatitis: global perspective and emerging science
por: Brar, Gurmehr, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8tb3nc9ka9pt85mqfaef5ffp6s