Designing Cyclic-Constrained Peptides to Inhibit Human Phosphoglycerate Dehydrogenase

Although loop epitopes at protein-protein binding interfaces often play key roles in mediating oligomer formation and interaction specificity, their binding sites are underexplored as drug targets owing to their high flexibility, relatively few hot spots, and solvent accessibility. Prior attempts to...

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Detalles Bibliográficos
Autores principales: Qing, Xiaoyu, Wang, Qian, Xu, Hanyu, Liu, Pei, Lai, Luhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563079/
https://www.ncbi.nlm.nih.gov/pubmed/37687259
http://dx.doi.org/10.3390/molecules28176430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563079/
https://www.ncbi.nlm.nih.gov/pubmed/37687259
http://dx.doi.org/10.3390/molecules28176430

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