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Designing Cyclic-Constrained Peptides to Inhibit Human Phosphoglycerate Dehydrogenase
Although loop epitopes at protein-protein binding interfaces often play key roles in mediating oligomer formation and interaction specificity, their binding sites are underexplored as drug targets owing to their high flexibility, relatively few hot spots, and solvent accessibility. Prior attempts to...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563079/ https://www.ncbi.nlm.nih.gov/pubmed/37687259 http://dx.doi.org/10.3390/molecules28176430 |