IGF1R Contributes to Cell Proliferation in ALK-Mutated Neuroblastoma with Preference for Activating the PI3K-AKT Signaling Pathway

SIMPLE SUMMARY: The insulin-like growth factor 1 receptor (IGF1R) is a receptor tyrosine kinase (RTK) widely expressed in many cancers, including the pediatric cancer neuroblastoma. Aberrant activation of the anaplastic lymphoma kinase (ALK) RTK by activating point mutations or amplification is iden...

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Detalles Bibliográficos
Autores principales: Guan, Jikui, Borenäs, Marcus, Xiong, Junfeng, Lai, Wei-Yun, Palmer, Ruth H., Hallberg, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563084/
https://www.ncbi.nlm.nih.gov/pubmed/37686528
http://dx.doi.org/10.3390/cancers15174252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563084/
https://www.ncbi.nlm.nih.gov/pubmed/37686528
http://dx.doi.org/10.3390/cancers15174252

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