Synthesis of N-alkoxycarbonyl Pyrroles from O-Substituted Carbamates: A Synthetically Enabling Pyrrole Protection Strategy

[Image: see text] The condensation of readily available O-substituted carbamates with 2,5-dimethoxytetrahydrofuran gives N-alkoxycarbonyl pyrroles in a single step and in good yield. By this method, several common amine protecting groups can be introduced on the pyrrole nitrogen. With the exception...

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Detalles Bibliográficos
Autores principales: Hann, Jodie L., Lyall, Catherine L., Kociok-Köhn, Gabriele, Lewis, Simon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563134/
https://www.ncbi.nlm.nih.gov/pubmed/37729493
http://dx.doi.org/10.1021/acs.joc.3c01257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563134/
https://www.ncbi.nlm.nih.gov/pubmed/37729493
http://dx.doi.org/10.1021/acs.joc.3c01257

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