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Core-Labeling (Radio) Synthesis of Phenols

[Image: see text] We report a method that enables the fast incorporation of carbon isotopes into the ipso carbon of phenols. Our approach relies on the synthesis of a 1,5-dibromo-1,4-pentadiene precursor, which upon lithium–halogen exchange followed by treatment with carbonate esters results in a fo...

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Detalles Bibliográficos
Autores principales: Lynch, Colin F., Downey, Joseph W., Zhang, Yongliang, Hooker, Jacob M., Levin, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563162/
https://www.ncbi.nlm.nih.gov/pubmed/37751441
http://dx.doi.org/10.1021/acs.orglett.3c02838