Kinetic parameters of alpha-synuclein seed amplification assay correlate with cognitive impairment in patients with Lewy body disorders

The alpha-synuclein (aSyn) seed amplification assay (SAA) can identify aSyn aggregates as indicator for Lewy body pathology in biomaterials of living patients and help in diagnosing Parkinson´s disease and dementia syndromes. Our objective was to confirm that qualitative results of aSyn SAA are repr...

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Detalles Bibliográficos
Autores principales: Bräuer, Stefan, Rossi, Marcello, Sajapin, Johann, Henle, Thomas, Gasser, Thomas, Parchi, Piero, Brockmann, Kathrin, Falkenburger, Björn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563218/
https://www.ncbi.nlm.nih.gov/pubmed/37814347
http://dx.doi.org/10.1186/s40478-023-01653-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563218/
https://www.ncbi.nlm.nih.gov/pubmed/37814347
http://dx.doi.org/10.1186/s40478-023-01653-3

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