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Knockout tales: the versatile roles of histone H3.3 in development and disease
Histone variant H3.3 plays novel roles in development as compared to canonical H3 proteins and is the most commonly mutated histone protein of any kind in human disease. Here we discuss how gene targeting studies of the two H3.3-coding genes H3f3a and H3f3b have provided important insights into H3.3...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563256/ https://www.ncbi.nlm.nih.gov/pubmed/37814296 http://dx.doi.org/10.1186/s13072-023-00512-8 |