Cargando…

Knockout tales: the versatile roles of histone H3.3 in development and disease

Histone variant H3.3 plays novel roles in development as compared to canonical H3 proteins and is the most commonly mutated histone protein of any kind in human disease. Here we discuss how gene targeting studies of the two H3.3-coding genes H3f3a and H3f3b have provided important insights into H3.3...

Descripción completa

Detalles Bibliográficos
Autores principales: Klein, Rachel H., Knoepfler, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563256/
https://www.ncbi.nlm.nih.gov/pubmed/37814296
http://dx.doi.org/10.1186/s13072-023-00512-8

Ejemplares similares