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CD8 cytotoxic T-cell infiltrates and cellular damage in the hypothalamus in human obesity

Rare cases of paraneoplastic obesity in children suggest sporadic obesity might also arise from an adaptive immune cell-mediated mechanism. Since the hypothalamus is a central regulator of feeding behavior and energy expenditure, we quantified lymphocytic inflammation in this region in a cohort of o...

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Detalles Bibliográficos
Autores principales: Ahrendsen, Jared T., Nong, Yi, Huo, Yuda, Steele, Jasmine, Anderson, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563257/
https://www.ncbi.nlm.nih.gov/pubmed/37814324
http://dx.doi.org/10.1186/s40478-023-01659-x