Abnormal adipogenic signaling in the bone marrow mesenchymal stem cells contributes to supportive microenvironment for leukemia development

BACKGROUND: Acute myeloid leukemia (AML) is an aggressive hematological malignancy, associated with unfavorable patient outcome, primarily due to disease relapse. Mesenchymal stem cells (MSCs) residing in the bone marrow (BM) niche are the source of mesenchyma-derived subpopulations, including adipo...

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Detalles Bibliográficos
Autores principales: Sabbah, Rawan, Saadi, Sahar, Shahar-Gabay, Tal, Gerassy, Shiran, Yehudai-Resheff, Shlomit, Zuckerman, Tsila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563260/
https://www.ncbi.nlm.nih.gov/pubmed/37817179
http://dx.doi.org/10.1186/s12964-023-01231-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563260/
https://www.ncbi.nlm.nih.gov/pubmed/37817179
http://dx.doi.org/10.1186/s12964-023-01231-z

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