Astragalus polysaccharide restores insulin secretion impaired by lipopolysaccharides through the protein kinase B /mammalian target of rapamycin/glucose transporter 2 pathway

BACKGROUND: Lipopolysaccharide (LPS)-induced dysfunction of pancreatic β-cells leads to impaired insulin (INS) secretion. Astragalus polysaccharide (APS) is a bioactive heteropolysaccharide extracted from Astragalus membranaceus and is a popular Chinese herbal medicine. This study aimed to elucidate...

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Detalles Bibliográficos
Autores principales: Ren, Xiaodan, Dai, Ying, Shan, Mengya, Zheng, Jing, Zhang, Zhongyi, Shen, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563267/
https://www.ncbi.nlm.nih.gov/pubmed/37817130
http://dx.doi.org/10.1186/s12906-023-04188-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563267/
https://www.ncbi.nlm.nih.gov/pubmed/37817130
http://dx.doi.org/10.1186/s12906-023-04188-1

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