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MAPK1 promotes the metastasis and invasion of gastric cancer as a bidirectional transcription factor
BACKGROUND: The Mitogen-activated protein kinase 1 (MAPK1) has both independent functions of phosphorylating histones as a kinase and directly binding the promoter regions of genes to regulate gene expression as a transcription factor. Previous studies have identified elevated expression of MAPK1 in...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10563293/ https://www.ncbi.nlm.nih.gov/pubmed/37817112 http://dx.doi.org/10.1186/s12885-023-11480-3 |